# # This file contains a matrix used for weighing the training sequences # when given an input sequence. Let z = (da, dc, dg, dt) be the vector # containing the differences in the relative nucleotide frequencies of # two sequences, the input sequence and a training sequence. # Then the training sequence has weight proportional to # # exp ( - z M z^t) # # with M being the matrix specified below. # If M is nonsingular, then (apart from a two normalizing factors) M # is the inverse of the covariance matrix of a multinormal # distribution - the kernel for the estimation. # this matrix is gc-content only, i.e. # weight = 10 * exp (-200 * (dc + dg))^2) # in particular weight <= 10 0 0 0 0 0 200 0 0 0 0 200 0 0 0 0 0